The copolymer of AMPS and other water-soluble monomers is an indispensable chemical in various paper mills. It can be used as a drainage aid, sizing agent, increasing the strength of paper, and also as a pigment dispersant for color coatings. Water soluble polymers containing AMPS can be used as paper strength enhancers, enhancing the utilization efficiency of fine pulp and fillers, dispersing agents for pulp in the papermaking process of inorganic substances such as paper, and improving the peeling efficiency of paper drying. In the paper production process, AMPS copolymers can be used to improve the retention rate of fillers and pulp debris, and increase the dehydration rate of pulp. Experiments have shown that adding water-soluble polymers containing AMPS as reinforcing agents to pulp significantly improves the relevant parameters of paper strength. At present, significant progress has been made in the application research of papermaking abroad, and research work in China has just begun, mainly in the research of AMPS copolymers. In the future development and research of papermaking additives in China, AMPS is an indispensable and important modified monomer.